Toward a Novel understanding of the function of dystrophin

Mina Petkova
Durée : 1276000
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Introduction
Dystrophin expression in various tissues
Generation of a dystrophin reporter mouse: Dmd
Dystrophin-EGFP in muscle tissue of Dmd mice
The muscle stem cells: satellite cells
DMD: a state of chronic injury and impaired regeneration
Muscle stem cells are responsible for regeneration
Loss of muscle stem cells leads to failed regeneration and loss of fibers
Dystrophin is expressed in activated satellite cells
Lack of dystrophin impairs satellite cell division and normal regeneration
Summary I
Recertant fibers (RFs): dystrophin positive fibers DMD patients
Understanding the RF-enigma : a dystrophic reporter mouse
Summary II
Acknowledgements
Questions - réponses
  • Introduction (0)
  • Dystrophin expression in various tissues (95000)
  • Generation of a dystrophin reporter mouse: Dmd (167000)
  • Dystrophin-EGFP in muscle tissue of Dmd mice (243000)
  • The muscle stem cells: satellite cells (404000)
  • DMD: a state of chronic injury and impaired regeneration (477000)
  • Muscle stem cells are responsible for regeneration (516000)
  • Loss of muscle stem cells leads to failed regeneration and loss of fibers (599000)
  • Dystrophin is expressed in activated satellite cells (639000)
  • Lack of dystrophin impairs satellite cell division and normal regeneration (701000)
  • Summary I (826000)
  • Recertant fibers (RFs): dystrophin positive fibers DMD patients (908000)
  • Understanding the RF-enigma : a dystrophic reporter mouse (1056000)
  • Summary II (1147000)
  • Acknowledgements (1191000)
  • Questions - réponses (1227000)
Mina Petkova

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